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Transcript

 

SPEAKER 1: The definition of very high risk patients-- first of all, diabetes is already a part of the definition of it. But in a diabetic patient with a prior cardiovascular event, even more if that cardiovascular event has been repeated over the time-- that is generally a patient which is considered at a very high risk.

So this other kind of patient, this kind of profiling-- a patient that already had a myocardial infarction, an acute coronary syndrome, they may already have had a stroke. And the combination of the two, considering that for each one of these categories in a diabetic individual, the risk is twice as much as compared to the same individual with the same number or kind of events, cardiovascular events-- I think that is the patient that should be really considered at a very, very high risk. And for that patient, again, we should really try to do our best.

And that's also because the residual risk in these patients is very high.

Video

Can you paint the profile of the post-ACS patient with T2D in whom the aggregate CV risk exceeds a threshold that supports a strategy of PCSK9-mediated LDL-C reduction in order to achieve levels of less than 70 mg/dL; or, even less than 50 mg/dL?

Can you paint the profile of the post-ACS patient with T2D in whom the aggregate CV risk exceeds a threshold that supports a strategy of PCSK9-mediated LDL-C reduction in order to achieve levels of less than 70 mg/dL; or, even less than 50 mg/dL?


Created by

CMEducation Resources IQ&A Cardiovascular Intelligence Zone | The Diabetes and Endocrinology Specialist's Perspective

Presenter

Stefano Del Prato, MD PhD

Stefano Del Prato, MD PhD

Professor of Endocrinology and Metabolism School of Medicine, University of Pisa Chief of the Section of Diabetes University of Pisa, Italy Clinical Associate Professor of Medicine University of Texas, San Antonio Health Science Center San Antonio, Texas